教师名录
司伟博士，副教授，硕士生导师，2020年度金年会信誉至上“至善青年学者”（B层次），江苏省2019年度优秀博士学位论文和金年会信誉至上2019年度优秀博士学位论文获得者，连续2年入选金年会信誉至上机械工程学院“优才培育计划”，担任《Materials International》(ISSN: 2668-5728)期刊助理编辑和《Bioengineering International》(ISSN 2668-7119)期刊编委，获得2019年Nanotechnology期刊杰出审稿人奖。
主要研究方向：微纳尺度下的（1）机械操控及机器人技术、（2）流体动力学及传感器、（3）结构工艺设计及加工制造、（4）程序语言算法和三维建模与仿真。
教学方面：获金年会信誉至上第28届青年教师授课竞赛二等奖（每年约前5%可入围），获首届金年会信誉至上教师教学创新大赛三等奖，作为项目负责人承担校级教改项目2项，已发表教改论文2篇，已录用教改论文1篇，担任金年会信誉至上机械工程学院本科生班主任，担任金年会信誉至上优秀生指导教师，担任本科生大类培养指导教师，担任铸造工艺大赛指导教师，所带的本科毕业设计获得金年会信誉至上2019 届本科生优秀毕业设计（论文）团队称号，所带本科生的毕业设计论文获得2019年、2021年机械学院优秀毕业设计论文,所带的本科生SRTP项目获得省级SRTP项目支持，所带的本科班级团支部获金年会信誉至上2020年“磐石计划”第二期校级项目立项。
科研方面：在Journal of the American Chemical Society、ACS Nano、Small、Small Methods等国内外期刊发表SCI论文44篇，EI论文19篇申请和授权发明专利11项，其中以第一作者在ACS Nano、Small、Small Methods等国内外期刊发表SCI论文22篇(包括IF>15.0的SCI论文6篇，封面论文3篇)。近年来作为主持人承担国家自然科学青年基金、江苏省基础研究计划（自然科学基金）青年基金、南京市留学人员科技创新项目、江苏省仪器仪表学会智能医疗器械创新基金和校企合作基金等多个项目；作为参与人参加研究国家重点研发计划1项，国家自然科学基金重点基金2项和面上基金3项。作为特邀报告，参加中国微米纳米技术学会第四届“微纳制造与微纳机器人技术”青年科学家论坛等并作大会报告。
个人学术主页1： https://www.researchgate.net/profile/Wei-Si-4/research
个人学术主页2： https://scholar.google.com/citations?user=J4R73XEAAAAJ&hl=en
五篇代表作（通讯作者论文加*）
1. Si, W.*;Yu, M.; Wu, G.;Chen, C.; Sha, J.; Zhang, Y.; Chen, Y.,A Nanoparticle-DNA Assembled Nanorobot Powered by Charge-Tunable Quad-Nanopore System. ACS Nano 2020, 14(11), 15349-15360. (IF：18.027)
2. Si, W.; Aksimentiev, A.,Nanopore Sensing of Protein Folding. ACSNano 2017,11 (7), 7091-7100. (IF：18.027)
3. Si, W. *; Zhang, Y.; Wu, G.;Kan, Y.; Zhang, Y.; Sha, J.; Chen, Y.,Discrimination of Protein Amino Acid or Its Protonated State at Single-Residue Resolution byGraphene Nanopores. Small 2019,15 (14), e1900036. (IF：15.153)
4. Si, W.*; Sun, Q.; Chen, C.; Yu, M.; Sha, J.; Zhang, Y.; Kan, Y.;Chen, Y., Detergent-Assisted Braking ofPeptide Translocation through a Single-Layer Molybdenum Disulfide Nanopore. Small Methods 2020, 1900822.( (IF：15.367，封面论文)
5. Si, W.*; Zhu, Z.; Wu, G.;Zhang, Y.; Chen, Y.; Sha, J. Encoding Manipulation of DNA‐NanoparticleAssembled Nanorobot Using Independently Charged Array Nanopores. Small Methods2022, n/a, 2200318. (IF：15.367)
欢迎优秀的本科生、研究生来课题组垂询体验（例如：竞赛、SRTP项目、毕业设计和攻读研究生学位等），课题组将为各位同学提供个性化的发展规划和优厚的助研津贴与绩效奖励，简历投递邮箱地址wei.si@seu.edu.cn。
2018年06月-2021年03月，金年会信誉至上，机械工程学院，讲师，硕导
2021年04月-至今，金年会信誉至上，机械工程学院，副教授，硕导
1.机械设计基础（56学时，本科生课程）
2.设计原理与方法II（48学时，本科生课程）
3.工程创新体验课（32学时，本科生课程）
4.微纳机电系统（全英文，48学时，本科生课程）
5.高等机构学（32学时，研究生课程）
1. ChemicalScience
2. ACSApplied Materials & Interfaces
3. ACSSensors
4. Nanotechnology
5. Journalof Physics D-Applied Physics
6. Journalof Physics-Condensed Matter
7. Langmuir
8. ModernPhysics Letters B
9. Electrophoresis
10. Polymer
11. IETNanobiotechnology
1.《MaterialsInternational》(ISSN: 2668-5728)期刊助理编辑
2.《BioengineeringInternational》(ISSN 2668-7119)期刊编委
1.2020年金年会信誉至上“至善青年学者”（B层次）
2.2020年Nanotechnology期刊最佳审稿人奖
3.2020年金年会信誉至上机械工程学院“优才培育计”
4.2019年金年会信誉至上机械工程学院“优才培育计”
5.2019年江苏省优秀博士学位论文
6.2019年金年会信誉至上优秀博士学位论文
第一作者或通讯作者教学论文（通讯作者论文加*）
1. 司伟*，工科专业课教学中“课程思政”与启发式教学的有机融合. 教书育人(高教论坛) 2021, 110-112.
2. 司伟*，工科专业课程中教师思政教学的意识培养与能力提升. 教书育人(高教论坛)2021, No.760, 45-47.
第一作者或通讯作者SCI论文（通讯作者论文加*）
1. Si, W.*; Zhu, Z.; Wu, G.;Zhang, Y.; Chen, Y.; Sha, J. Encoding Manipulation of DNA‐NanoparticleAssembled Nanorobot Using Independently Charged Array Nanopores. Small Methods 2022,n/a, 2200318.
2. Si, W.*; Yuan, R.; Wu, G.; Kan,Y.; Sha, J.; Chen, Y.; Zhang, Y.; Shen, Y. Navigated Delivery of Peptide to theNanopore Using In-Plane Heterostructures of MoS2 and SnS2 for ProteinSequencing. J. Phys. Chem. Lett. 2022, 3863-3872.
3. Yu,M. #; Si, W. *#（#并列一作）; Zeng, T. #; Chen, C.; Lin, X.;Ji, Z.; Guo, F.; Li, Y.; Sha, J.; Dong, Y. Unveiling the Microscopic Mechanismof Current Variation in the Sensing Region of the MspA Nanopore for DNASequencing. J. Phys. Chem. Lett. 2021, 9132-9141.
4. Si, W.*; Yang, H.; Wu, G.;Zhang, Y.; Sha, J. Velocity control of protein translocation through a nanoporeby tuning the fraction of benzenoid residues. Nanoscale 2021.
5. Si, W.*; Chen, C.; Wu, G.; Sun,Q.; Yu, M.; Qiao, Y.; Sha, J. High Efficient Seawater Desalination Based onParallel Nanopore Systems. Nano 2021, 16, 2150077.
6. Si, W.*;Yu, M.; Wu, G.;Chen, C.; Sha, J.; Zhang, Y.; Chen, Y.,A Nanoparticle-DNA Assembled Nanorobot Powered by Charge-Tunable Quad-Nanopore System. ACS Nano 2020, 14(11), 15349-15360.
7. Si, W.*; Sun, Q.; Chen, C.; Yu, M.; Sha, J.; Zhang, Y.; Kan, Y.;Chen, Y., Detergent-Assisted Braking ofPeptide Translocation through a Single-Layer Molybdenum Disulfide Nanopore. Small Methods 2020, 1900822.(封面论文)
8. Si, W.*; Yang, H.; Wu, G.; Chen, C.; Yu, M., Manipulation of DNAtransport through solid-state nanoporesby atomic force microscopy. Materials Research Express 2020,7 (9), 095404.
9. Liu,C. #; Si, W. #（#并列一作）; Wu, C.#; Yang, J.; Chen, Y.; Dames, C., The ignored effects ofvibrational entropy and electrocaloriceffect in PbTiO3 and PbZr0.5Ti0.5O3 as studied through first-principles calculation. Acta Materialia2020,191, 221-229.
10. Si, W.; Sha, J.; Sun, Q.; He,Z.; Wu, L.; Chen, C.; Yu, S.-H.; Chen,Y., Shape Characterization and Discrimination of Single Nanoparticles using Solid-state Nanopores.Analyst 2020,145 (5), 1657-1666. (封面论文)
11. Si, W.*; Liu, C.; Sha, J.;Zhang, Y.; Chen, Y., Computational modeling of ionic currents through difform graphene nanopores withconsistent cross-sectional areas. Phys.Chem. Chem. Phys. 2019,21 (47),26166-26174.
12. Si, W. *; Zhang, Y.; Wu, G.;Kan, Y.; Zhang, Y.; Sha, J.; Chen, Y.,Discrimination of Protein Amino Acid or Its Protonated State at Single-Residue Resolution byGraphene Nanopores. Small 2019,15 (14), e1900036.
13. Si, W.; Yang, H.; Sha, J.;Zhang, Y.; Chen, Y., Discrimination ofsingle-stranded DNA homopolymers by sieving out G-quadruplex using tiny solid-state nanopores. Electrophoresis2019,40 (16-17), 2117-2124.(封面论文)
14. Si, W. *; Zhang, Y.; Sha, J. J.;Chen, Y. F., Mechanisms ofpressure-induced water infiltration process through graphene nanopores. Mol Simulat 2019,45 (6),518-524.
15. Si, W.*; Zhang, Y.; Sha, J.;Chen, Y., Controllable and reversibleDNA translocation through a single-layer molybdenum disulfide nanopore. Nanoscale 2018,10 (41), 19450-19458.
16. Sha,J.#; Si, W.#（#并列一作）; Xu, B.; Zhang, S.; Li, K.; Lin, K.; Shi, H.; Chen, Y., Identificationof Spherical and Nonspherical Proteinsby a Solid-State Nanopore. Anal. Chem. 2018,90 (23), 13826-13831.
17. Si, W.; Yang, H. J.; Li, K.;Wu, G. S.; Zhang, Y.; Kan, Y. J.; Xie,X.; Sha, J. J.; Liu, L.; Chen, Y. F., Investigation on the interaction length and access resistance of ananopore with an atomic forcemicroscopy. Science China-TechnologicalSciences 2017,60 (4), 552-560.
18. Si, W.; Aksimentiev, A.,Nanopore Sensing of Protein Folding. ACSNano 2017,11 (7), 7091-7100.
19. Si, W.; Aksimentiev, A.,Nanopore Ionic Current can Report on theFolding State of a Protein. Biophys. J. 2017,112 (3), 195a-195a.
20. Cressiot,B.#; Greive, S. J.#; Si, W#.（#并列一作）; Pascoa, T. C.; Mojtabavi,M.; Chechik, M.; Jenkins, H. T.; Lu, X.;Zhang, K.; Aksimentiev, A.; Antson, A. A.; Wanunu, M., Porphyrin-Assisted Docking of a Thermophage PortalProtein into Lipid Bilayers: NanoporeEngineering and Characterization. ACS Nano 2017,11 (12), 11931-11945.
21. Si, W.; Zhang, Y.; Wu, G. S.;Sha, J. J.; Liu, L.; Chen, Y. F., DNAsequencing technology based on nanopore sensors by theoretical calculations and simulations. Chinese ScienceBulletin 2014,59 (35), 4929-4941.
22. Si, W.; Sha, J. J.; Liu, L.;Qiu, Y. H.; Chen, Y. F., Effect ofnanopore size on poly(dT)(30) translocation through silicon nitride membrane. Sci. China: Technol. Sci. 2013,56 (10), 2398-2402.
第一作者或通讯作者EI论文（通讯作者论文加*）
23. Yu,M.; Si, W.*; Sha, J. InMolecular Dynamics Simulation for Protein Unfolding, 2020 IEEE 15thInternational Conference on Nano/Micro Engineered and Molecular System (NEMS),27-30 Sept. 2020; 2020; pp 382-386.
24. Si, W.; Yang, H.; Ji, A.; Li,K.; Sha, J.; Liu, L.; Chen, Y.,Electrophoresis of poly(dT)20 through alpha-hemolysin nanopore in high concentration potassium chloridesolution. Journal of Southeast University (English Edition) 2016,32 (4), 496-501.
25. Si, W.; Sha, J.; Liu, L.;Zhang, Y.; Chen, Y. In The moleculardynamics study for detection of ssDNA bymonolayer graphene nanopore, ASME 2013 InternationalMechanical Engineering Congress and Exposition, IMECE 2013, November 15, 2013 - November 21, 2013, SanDiego, CA, United states, American Society of Mechanical Engineers (ASME): San Diego, CA, United states, 2013;p V03AT03A046.
26. Si, W.; Sha, J. J.; Liu, L.;Li, J. P.; Wei, X. L.; Chen, Y. F.,Detecting DNA Using a Single Graphene Pore by Molecular Dynamics Simulations. Micro-Nano Technology Xiii 2012,503, 423-426.
其他SCI论文
27. Zhan,L.; Zhang, Y.; Si, W.; Sha,J.; Chen, Y. Detection and Separation of Single-Stranded DNA Fragments UsingSolid-State Nanopores. J. Phys. Chem. Lett. 2021, 12, 6469-6477.
28. Zhang,Y.; Zhao, J.; Si, W.; Kan,Y.; Xu, Z.; Sha, J.; Chen, Y. Electroosmotic Facilitated Protein Capture andTransport through Solid‐State Nanopores with Diameter Larger than Length. SmallMethods 2020, 4, 1900893.
29. Zhang,Y.; Zhao, J.; Kan, Y.; Ji, R.; Pan, J.; Huang, W.; Xu, Z.; Si, W.; Sha, J. Concentration effects on capture rate andtranslocation configuration of nanopore-based DNA detection. Electrophoresis2020, 41, 1523-1528.
30. Wilson,J.; Sarthak, K.; Si, W.; Gao,L.; Aksimentiev, A. Rapid and Accurate Determination of Nanopore Ionic CurrentUsing a Steric Exclusion Model. ACS Sens 2019, 4, 634-644.
31. Ma,J.; Li, K.; Li, Z.; Qiu, Y.; Si, W.;Ge, Y.; Sha, J.; Liu, L.; Xie, X.; Yi, H.; Ni, Z.; Li, D.; Chen, Y. DrasticallyReduced Ion Mobility in a Nanopore Due to Enhanced Pairing and Collisionsbetween Dehydrated Ions. J. Am. Chem. Soc. 2019, 141, 4264-4272.
32. Yang,H.; Li, Z.; Si, W.; Lin, K.;Ma, J.; Li, K.; Sun, L.; Sha, J.; Chen, Y. Identification of Single Nucleotidesby a Tiny Charged Solid-State Nanopore. J. Phys. Chem. B 2018, 122, 7929–7935.
33. Winogradoff,D.; Maffeo, C.; Si, W.;Aksimentiev, A. All-Atom Structure and Ionic Conductivity of the Nuclear PoreComplex. Biophys. J. 2018, 114, 630a-630a.
34. Shi,X.; Li, Q.; Gao, R.; Si, W.;Liu, S. C.; Aksimentiev, A.; Long, Y. T. Dynamics of a Molecular Plug Dockedonto a Solid-State Nanopore. J. Phys. Chem. Lett. 2018, 9, 4686-4694.
35. Zhang,Y.; Wu, G.; Si, W.; Ma, J.;Yuan, Z.; Xie, X.; Liu, L.; Sha, J.; Li, D.; Chen, Y. Ionic current modulationfrom DNA translocation through nanopores under high ionic strength andconcentration gradients. Nanoscale 2017, 9, 930-939.
36. Yang,H. J.; Li, Z. W.; Chen, Y. F.; Si, W.Identification of Single Nucleotides in SiN Nanopore. Biophys. J. 2017, 112,25a-25a.
37. Wolfe,A. J.; Si, W.; Zhang, Z.;Blanden, A. R.; Hsueh, Y. C.; Gugel, J. F.; Pham, B.; Chen, M.; Loh, S. N.;Rozovsky, S.; Aksimentiev, A.; Movileanu, L. Quantification of MembraneProtein-Detergent Complex Interactions. J. Phys. Chem. B 2017, 121,10228-10241.
38. Shi,X.; Gao, R.; Ying, Y. L.; Si, W.;Chen, Y. F.; Long, Y. T. A Scattering Nanopore for Single Nanoentity Sensing.Acs Sensors 2016, 1, 1086-1090.
39. Cao,Y.; Lin, Y.; Qian, R. C.; Ying, Y. L.; Si,W.; Sha, J.; Chen, Y.; Long, Y. T. Evidence of single-nanoparticletranslocation through a solid-state nanopore by plasmon resonance energytransfer. Chem. Commun. (Camb.) 2016, 52, 5230-3.
40. Shi,X.; Gao, R.; Ying, Y. L.; Si, W.;Chen, Y.; Long, Y. T. An integrated system for optical and electrical detectionof single molecules/particles inside a solid-state nanopore. Faraday Discuss.2015, 184, 85-99.
41. Sha,J. J.; Si, W.; Xu, W.; Zou,Y. R.; Chen, Y. F. Glass capillary nanopore for single molecule detection.Science China-Technological Sciences 2015, 58, 803-812.
42. Qiu,Y. H.; Li, K.; Chen, W. Y.; Si, W.;Tan, Q. Y.; Chen, Y. F. Ion and water transport in charge-modified graphenenanopores. Chinese Physics B 2015, 24, 108201.
43. Kan,Y.; Tan, Q.; Wu, G.; Si, W.;Chen, Y. Study of DNA adsorption on mica surfaces using a surface forceapparatus. Sci. Rep. 2015, 5, 8442.
44. Zhang,Y.; Wu, G. S.; Si, W.; Sha,J. J.; Liu, L.; Chen, Y. F. Retarding and manipulating of DNA molecules translocationthrough nanopores. Chin. Sci. Bull. 2014, 59, 4908-4917.
45. Zhang,Y.; Wu, G.; Ma, J.; Yuan, Z.; Si, W.;Liu, L.; Sha, J.; Chen, Y. Temperature effect on translocation speed andcapture rate of nanopore-based DNA detection. Sci China Technol Sc 2014, 58,519-525.
46. Wu,G. S.; Zhang, Y.; Si, W.;Sha, J. J.; Liu, L.; Chen, Y. F. Integrated solid-state nanopore devices forthird generation DNA sequencing. Science China-Technological Sciences 2014, 57,1925-1935.
47. Qiu,Y. H.; Tan, Q. Y.; Si, W.;Chen, Y. F. Ion specificity in NaCl solution confined in silicon nanochannels.Science China-Technological Sciences 2014, 57, 230-238.
其他EI或会议论文
48. Ji,Y.; Wang, Y.; Si, W.; Chen,Y. In Molecular dynamics study on the effect of lipid membrane mechanicalproperties on the interaction between β-amyloid and lipid membrane, 2020 14thInternational Conference on Signal Processing and Communication Systems(ICSPCS), 14-16 Dec. 2020; 2020; pp 1-6.
49. Sun,Q.; Si, W.; Sha, J.; Chen, Y.In Size Characterization of Single Nanoparticles Using Solid-state Nanopores,2019 IEEE International Conference on Manipulation, Manufacturing andMeasurement on the Nanoscale (3M-NANO), 4-8 Aug. 2019; 2019; pp 316-319.
50. Chen,C.; Si, W.; Wang, G.; Qiao,Y.; Sun, Q.; Sha, J. In MD Simulation for A Double Nanopore DesalinationSystem, 2019 IEEE International Conference on Manipulation, Manufacturing andMeasurement on the Nanoscale (3M-NANO), 4-8 Aug. 2019; 2019; pp 312-315.
51. Yang,H. J.; Si, W.; Ji, A. P.;Sha, J. J.; Chen, Y. F.; Xie, X.; Ji, A. P.; Ieee, Double Layer NanoporeFabricated by FIB and TEM. In 2017 Ieee International Conference onManipulation, Manufacturing and Measurement on the Nanoscale, Ieee: New York,2017; pp 274-277.
52. Yu,J.; Si, W.; Sha, J.; Chen, Y.Effect of salt gradients on DNA translocation through solid-state nanopores.Journal of Southeast University (English Edition) 2016, 32, 307-311.
53. Wu,G.; Zhang, Y.; Si, W.; Gu,Y.; Chen, Y. Current blockade mechanism for DNA translocation throughsolid-state nanopore with different membrane thickness. Journal of SoutheastUniversity (English Edition) 2016, 32, 301-306.
54. Li,K.; Yuan, Z.; Ji, A.; Si, W.;Lin, K.; Yang, H.; Ma, J.; Sha, J.; Chen, Y. Electrokinetics transport ofconfined electrolyte solution in high concentration. Dongnan Daxue Xuebao(Ziran Kexue Ban)/Journal of Southeast University (Natural Science Edition)2016, 46, 972-976.
55. Haojie,Y.; Duan, Z.; Si, W.; Li, K.;Chen, Y. In Influence of solution Ph on DNA translocation velocity throughalumina nanopores, ASME 2016 International Mechanical Engineering Congress andExposition, IMECE 2016, November 11, 2016 - November 17, 2016, Phoenix, AZ,United states, American Society of Mechanical Engineers (ASME): Phoenix, AZ,United states, 2016; p American Society of Mechanical Engineers (ASME).
56. Cai,D.; Kan, Y.; Zhao, G.; Wu, G.; Si, W.;Tan, Q.; Chen, Y. Adsorption and desorption behaviors of ssDNA molecules onmica surface by surface forces apparatus. Journal of Southeast University(English Edition) 2016, 32, 45-50.
57. Zhang,Y.; Wu, G.; Si, W.; Sha, J.;Liu, L.; Chen, Y. In Nanopore positive pulse detection of DNA with saltgradients, International Conference on Machining, Materials and MechanicalTechnologies, IC3MT 2014, August 31, 2014 - September 5, 2014, Taipei City, Taiwan,Trans Tech Publications Ltd: Taipei City, Taiwan, 2015; pp 567-572.
58. Sha,J.; Si, W.; Zhang, Y.; Chen,Y. In Concentration gradient effect on the capturing ratio of nanopore for DNA,International Conference on Machining, Materials and Mechanical Technologies,IC3MT 2014, August 31, 2014 - September 5, 2014, Taipei City, Taiwan, TransTech Publications Ltd: Taipei City, Taiwan, 2015; pp 554-560.
59. Li,K.; Si, W.; Sha, J.; Chen, Y.In Molecular dynamics study of DNA translocation through graphene nanoporeswith controllable speed, ASME 2015 International Mechanical EngineeringCongress and Exposition, IMECE 2015, November 13, 2015 - November 19, 2015,Houston, TX, United states, American Society of Mechanical Engineers (ASME):Houston, TX, United states, 2015; p American Society of Mechanical Engineers(ASME).
60. Li,K.; Sha, J. J.; Liu, L.; Wu, G. S.; Si,W.; Chen, Y. F. In Molecular Dynamics Study of Confined Fluid inGraphene Nanopores, Advanced Materials Research, Trans Tech Publ: 2015; pp205-208.
61. Zhang,Y.; Liu, L.; Sha, J.; Si, W.;Ma, J.; Chen, Y. In Fabrication of Al2O3 nanopore sensors for DNA detection,ASME 2013 International Mechanical Engineering Congress and Exposition, IMECE2013, November 15, 2013 - November 21, 2013, San Diego, CA, United states,American Society of Mechanical Engineers (ASME): San Diego, CA, United states,2013; p ASME.
62. Qiu,Y.; Ma, J.; Guo, W.; Si, W.;Tan, Q.; Chen, Y. In Ionic current investigation in silicon nanochannels withmolecular dynamics simulations, 2013 International Conference on Manipulation,Manufacturing and Measurement on the Nanoscale, 3M-NANO 2013, August 26, 2013 -August 30, 2013, Suzhou, China, IEEE Computer Society: Suzhou, China, 2013; pp325-328.
1. 司伟，林晓静，沙菁㛃，陈云飞。一种履带式纳米小车及其控制、制备方法。发明专利：202210355100.0，2022。（申请）
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9. 沙菁㛃，张志诚，陈云飞，孙倩怡，傅方舟，司伟，章寅。纳米孔检测芯片的便携式装夹装置。发明专利：2018113280206，2019。（授权）
10. 沙菁㛃，孙倩怡，张志诚，傅方舟，陈云飞，司伟，章寅。一种光控纳米孔的单分子可控输出装置及其使用方法。发明专利：2018111864636，2018。（申请）
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